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Description

The oxidative stress was increased in type II Diabetes mellitus

What nutritional modifications or additional supplementation might be necessary

Pierozan et al

iron overload in epileptic foci promotes the generation of lipid peroxides through ACSL4-mediated arachidonic acid metabolism, while decreased GPX4 activity further weakens antioxidant defenses, forming a vicious cycle of neuronal hyperexcitability-oxidative stress. Preclinical studies show that using Liproxstatin-1 to inhibit ferroptosis can significantly reduce the frequency of seizures and protect hippocampal neurons (Batista et al., 2021)